STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU -- MARCAINE HYDROCHLORIDE  -- 6850-00F048759
<pre>=====================  Product Identification  =====================

Product ID:MARCAINE HYDROCHLORIDE
MSDS Date:05/07/1993
FSC:6850
NIIN:00F048759
=== Responsible Party ===
Company Name:STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU
Address:90 PARK AVE
City:NEW YORK
State:NY
ZIP:10016-1302
Country:US
Info Phone Num:212-907-2000/800-223-5511
Emergency Phone Num:212-907-2000/800-223-5511
CAGE:GO573
=== Contractor Identification ===
Company Name:STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU
Address:90 PARK AVE
City:NEW YORK
State:NY
ZIP:10016-1302
Country:US
Phone:212-907-2000/800-223-5511
CAGE:GO573
Company Name:WINTHROP PHARMACEUTICALS
Address:90 PARK AVE
Box:City:NEW YORK
State:NY
ZIP:10156
Country:US
Phone:212-907-2000
CAGE:63240

=============  Composition/Information on Ingredients  =============

Ingred Name:BUPIVACAINE HYDROCHLORIDE, MARCAINE HYDROCHLORIDE  *96-2*
CAS:14252-80-3
RTECS #:TK6125000

Ingred Name:BUPIVACAINE HYDROCHLORIDE
CAS:18010-40-7
Fraction by Wt: <1%

Ingred Name:WATER
CAS:7732-18-5
RTECS #:ZC0110000
Fraction by Wt: >25%

=====================  Hazards Identification  =====================

Routes of Entry: Inhalation:NO	Skin:NO  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:OVERDOSE, MAY CAUSE ADVERSE CNS,
    CARDIOVASCULAR SYSTEM, ALLERGIC & NEUROLOGICAL REACTIONS. SYSTEMIC
    DOSE-RELATED TOXICITY, UNDERVENTILATION, APNEA & RESPIRATORY
    PARALYSIS MAY OCCUR, WHICH CAN LEAD TO  CARDIAC ARREST.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:RESTLESSNESS, ANXIETY, INCOHERENT SPEECH,
    LIGHTHEADEDENESS, NUMBNESS, TINGLING OF THE MOUTH & LIPS, METALLIC
    TASTE, TINNITUS, DIZZINESS, BLURRED VISION, TREMORS, TWITCHING,
    DEPRESSION, DROWSINESS.

=======================  First Aid Measures  =======================

First Aid:EYES: FLUSH W/PLENTY OF WATER FOR 15 MINS. SKIN: WASH
    THOROUGHLY W/SOAP & WATER. OBTAIN MEDICAL ATTENTION IN ALL CASES.
    NOTE TO PHYSICIAN: DELAY IN PROPER DOSE-RELATED TOXICITY,
    UNDERVENTILATION FROM  ANY CAUSE &/ALTERED SENSITIVITY MAY LEAD TO
    THE DEVELOPMENT OF ACIDOSIS, CARDIAC ARREST & POSSIBLY DEATH.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:USE ANY EXTINGUISHING AGENT SUITABLE FOR
    SURROUNDING FIRE.
Fire Fighting Procedures:USE NORMAL FIRE FIGHTING GEAR.

==================  Accidental Release Measures  ==================

Spill Release Procedures:USE RUBBER/PLASTIC GLOVES. CONTAIN BY PLACING
    PAPER TOWELS/A SUITABLE ABSORBENT MATERIAL AROUND THE EDGES OF THE
    AREA & WORK INWARD. CAREFULLY SCOOP UP INTO A PROPERLY LABELED
    WASTE CONTAINER FOR DISP OSAL. WASH AREA TO REMOVE FROM SURFACES.

======================	Handling and Storage  ======================

Handling and Storage Precautions:KEEP THIS & ALL DRUGS OUT OF THE REACH
    OF CHILDREN.
Other Precautions:AVOID EYE CONTACT.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NONE NORMALLY REQUIRED.
Ventilation:NORMAL
Protective Gloves:NONE NORMALLY REQUIRED.
Eye Protection:NONE NORMALLY REQUIRED.
Work Hygienic Practices:USE GOOD PERSONAL HYGIENE. WASH HANDS & EXPOSED
    SKIN THOROUGHLY W/SOAP & WATER AFTER USE.
Supplemental Safety and Health

==================  Physical/Chemical Properties  ==================

Solubility in Water:COMPLETE
Appearance and Odor:COLORLESS LIQUID

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
    REGULATIONS.

 Disclaimer (provided with this information by the compiling agencies):
 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
 assume responsibility for the suitability of this information to their
 particular situation.